![]() Only English language articles were considered, and all studies were limited to LIESWT and ED only.Īvailable literature was reviewed, and relevant studies were analysed, summarized and presented at the Micro-Energy LIESWT forum at the recent scientific meeting of the Asia Pacific Society for Sexual Medicine in 2019. The following terms “low intensity shock wave therapy”, “low intensity pulsed ultrasound”, “erectile dysfunction”, “shock wave machine”, “neovascularization”, “erectile function”, “penile hemodynamic”, “clinical outcome”, and “safety” were used to search several databases including MEDLINE and EMBASE for inclusion in this article. ![]() This clinical guideline provides a brief overview of the basic technology and technical aspects on shockwave machines, as well as summary recommendations on the clinical use of LIESWT and LIPUS in ED based on published literature in ED. Published literature on the regenerative properties of low intensity extracorporeal shockwave therapy (LIESWT) and low intensity pulsed ultrasound (LIPUS) are exciting and potentially offer many men the opportunity to regain spontaneous erection again. Shock wave therapy has been used to treat stone disease for more than 4 decades and over the years, significant scientific advances have been made to miniaturize and improve shock wave technology so that it can be applied to treat other medical conditions. On the other hand, penile prosthesis implant is an irreversible treatment option and men will not be able to regain spontaneous erection again despite explant of this device. The contemporary medical treatment does not significantly alter the underlying pathophysiology of erectile mechanism, improve endothelial dysfunction or restore underlying physiological erectile function (EF). More stringent and larger multi-institutional randomised placebo-controlled trials are warranted before clinical adoption of LIESWT and LIPUS as the new standard of care for men with ED.Ĭlinical studies showed that erectile dysfunction (ED) is a common condition that has an adverse impact on various physical and psychosocial domains. ![]() There is a need to better define which subgroup of ED population is best-suited, and specific treatment protocol to optimise shock wave energy delivery. However, controversial exists due to sampling heterogeneity, non-standardised treatment protocol and lack of large multiinstitutional studies. Existing literature supports the use of LIESWT and LIPUS in men with ED, with many clinical studies reported encouraging results with improved erectile function, good safety profile and short-term durability. ![]() The clinical findings were internally discussed, and the quality of evidence was graded based on the Oxford Centre for Evidence-Based Medicine recommendations. Key opinion leaders across the Asia Pacific region attended the recent biennial meeting of the Asia Pacific Society for Sexual Medicine in Australia, and presented the current evidence on LIESWT and LIPUS for erectile dysfunction (ED). Published literature shows low intensity extracorporeal shock wave therapy (LIESWT) and low intensity pulsed ultrasound (LIPUS) therapy to improve erectile function and penile hemodynamic by inducing neovascularisation and promoting tissue regeneration.
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